Journal of Medicinal Chemistry p. 2866 - 2879 (1995)
Update date:2022-07-29
Topics:
Olson, Gary L.
Cheung, Ho-Chuen
Chiang, Elliot
Madison, Vincent S.
Sepinwall, Jerry
et al.
The design and synthesis of peptide mimetics of thyrotropin-releasing hormone (TRH) in which the peptide backbone is entirely replaced by a cyclohexane framework are described.The cis-1,3,5-trisubstituted ring was expected to permit key pharmacophoric gro
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