A versatile asymmetric synthesis of α-amino α-alkyl-phosphonic acids of high enantiomeric purity

DOI: 10.1016/S0040-4039(00)97092-8

Source and publish data:

Tetrahedron Letters p. 6465 - 6468 (1990)

Update date:2022-07-29

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Authors:

Hanessian, Stephen

Bennani, Youssef L.

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Article abstract of DOI:10.1016/S0040-4039(00)97092-8

A general protocol for the synthesis of α-amino-α- alkyl phosphonic acids in either enantiomeric form is described based on the alkylation of chiral bicyclic phosphonamides derived from (R,R)- and (S,S)-1,2-diaminocyclohexane.

Full text of DOI:10.1016/S0040-4039(00)97092-8

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