REACTION OF Δ3-PYRROLINES WITH DIMETHYL ACETYLENEDICARBOXYLATE. A NOVEL PYRROLE FORMING REARRANGEMENT

Article abstract of DOI:10.1016/S0040-4039(01)91159-1

Reaction of arylidene imines of methyl phenylglycinate with 2 moles of dimethyl acetylenedicarboxylate (ADE) leads, via an intermediate Δ³-pyrroline, to loss of the original methyl phenylglycinate moiety and formation of 2-aryl-3,4,5-tricarbo methoxypyrroles.