Highly stereoselective synthesis of α-hydroxy β-amino acids through β-lactams: Application to the synthesis of the taxol and bestatin side chains and related systems

Article abstract of DOI:10.1016/S0040-4039(00)97083-7

Formation of α-hydroxy β-lactams, followed by chemical elaboration at C₄ and further β-lactam cleavage afforded functionalised α-hydroxy β-amino acids or their derivatives in a highly stereoselective manner.