Journal of Medicinal Chemistry p. 491 - 496 (1991)
Update date:2022-08-03
Topics:
Rewcastle, Gordon W.
Atwell, Graham J.
Palmer, Brian D.
Boyd, Peter D. W.
Baguley, Bruce C.
Denny, William A.
A series of tricyclic analogues of 9-oxo-9H-xanthene-4-acetic acid have been prepared and evaluated for their ability to cause homorrhagic necrosis in subcutaneously implanted colon 38 tumors in mice, in an effort to extend the structure-activity relation
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