Synthesis and antimicrobial activity of 2'-deoxypuromycin.

Article abstract of DOI:10.1080/00021369.1990.10870451

2'-Deoxypuromycin (2) was synthesized to learn the effect of the 2'-hydroxyl group on the biological activity. Acylated xylose 3 was condensed with silylated 6-chloropurine to give beta-D-xylofuranosyl-6-chloropurine derivative 4, whose 6-dimethylaminatio

Full text of DOI:10.1080/00021369.1990.10870451

This article was downloaded by: [Cornell University Library]
On: 16 November 2014, At: 18:55
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered
office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK
Agricultural and Biological Chemistry
Publication details, including instructions for authors and
subscription information:
http://www.tandfonline.com/loi/tbbb19
Synthesis and Antimicrobial Activity of
2′-Deoxypuromycin
Fumiaki Koizumia, Takayuki Oritania & Kyohei Yamashitaa
a Department of Agricultural Chemistry, Faculty of Agriculture,
Tohoku University, Aoba-ku, Sendai 981, Japan
Published online: 08 Sep 2014.
To cite this article: Fumiaki Koizumi, Takayuki Oritani & Kyohei Yamashita (1990) Synthesis
and Antimicrobial Activity of 2′-Deoxypuromycin, Agricultural and Biological Chemistry, 54:12,
3093-3097
To link to this article: http://dx.doi.org/10.1080/00021369.1990.10870451
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the information (the
“Content”) contained in the publications on our platform. However, Taylor & Francis,
our agents, and our licensors make no representations or warranties whatsoever as to
the accuracy, completeness, or suitability for any purpose of the Content. Any opinions
and views expressed in this publication are the opinions and views of the authors,
and are not the views of or endorsed by Taylor & Francis. The accuracy of the Content
should not be relied upon and should be independently verified with primary sources
of information. Taylor and Francis shall not be liable for any losses, actions, claims,
proceedings, demands, costs, expenses, damages, and other liabilities whatsoever
or howsoever caused arising directly or indirectly in connection with, in relation to or
arising out of the use of the Content.
This article may be used for research, teaching, and private study purposes. Any
substantial or systematic reproduction, redistribution, reselling, loan, sub-licensing,
systematic supply, or distribution in any form to anyone is expressly forbidden. Terms &
Conditions of access and use can be found at http://www.tandfonline.com/page/terms-
and-conditions