DIASTEREOSPECIFIC SYNTHESIS OF (-)-STATINE

DOI: 10.1016/S0040-4039(00)88557-3

Source and publish data:

Tetrahedron Letters p. 7329 - 7332 (1990)

Update date:2022-08-04

Topics:

Authors:

Ohta, Tomihisa

Shiokawa, Sojiro

Sakamoto, Rumiko

Nozoe, Shigeo

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Article abstract of DOI:10.1016/S0040-4039(00)88557-3

Reductive deoxygenation at quarternary α-carbon of α-hydroxy lactam was found to preceed under mild condition.Making an advantage of this procedure, (-)-statine was synthesized from L-malic acid in a diastereospecific manner.

Full text of DOI:10.1016/S0040-4039(00)88557-3

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