
Tetrahedron Letters p. 7485 - 7488 (1990)
Update date:2022-08-02
Topics:
Marriott, Jonathan H.
Mottahedeh, Mina
Reese, Colin B.
Treatment of 5'-chloro-5'-deoxynucleosides (5) with the conjugate base of 9-(4-methoxyphenyl)xanthen-9-thiol (3b), followed by acid-promoted removal of the 5'-S-<9-(4-methoxyphenyl)xanthen-9-yl> group in the presence of pyrrole gives the corresponding 5'-deoxy-5'-mercaptonucleosides (7) in good yields.
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