Journal of Crystallographic and Spectroscopic Research p. 1 - 8 (1991)
Update date:2022-08-02
Topics:
Kozerski, L.
Kawecki, R.
Urbanczyk-Lipkowska, Z.
Krajewski, J.W.
Gluzinski, P.
The structure of the title compound has been investigated in the solid state and in solution by X-ray and NMR-NOE methods, respectively.The crystals are monoclinic: P21/c, a = 9.828(1), b = 12.326(2), c = 13.976(2) Angstroem, β = 107.36(1) deg.The structure was solved by direct methods, and refined against 2495 unique reflections by a full-matrix, least-squares procedure giving R = 0.046.In the solid state the compound exists as the E isomer with unlike relative configurations on asymmetric atoms.In solution the compound is found as a mixture of a single enamine and two imine forms.The MM calculations suggest that of the two possible geometrical isomers of both diastereoisomers u and l of the enamine, the Z forms should be of lower energy.The total recognition of the homonuclear 1H NMR-NOE data interpreted in terms of their distance dependence in the two geometrical forms also favors the Z isomer in both diastereomers.
View MoreContact:+36(21)2523420
Address:Head office: 1102 Budapest, SZENT LASZLO TER 24/B. 1/1., HUNGARY / CHINA
Contact:+ 86 512 52491118
Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Chengdu Gelipu Biotechnology Co., Ltd.
website:http://www.glp-china.com
Contact:86-28-82610909
Address:chegndu
YanCheng LongShen Chemical Co.,Ltd.
Contact:+86-515-86668866
Address:No.13,Weiyi Road,Funing Aoyang Industrial Park
Shandong Ailitong New Material Co.,Ltd
Contact:+86-536-3226266
Address:zhongjia village, putong town , qingzhou city,Shandong Province,China
Doi:10.1021/jo00006a060
(1991)Doi:10.1021/jm00109a005
(1991)Doi:10.1016/j.tet.2011.07.067
(2011)Doi:10.1016/S0040-4020(01)87932-1
(1990)Doi:10.1007/s10637-009-9309-6
(2010)Doi:10.3987/COM-12-12640
(2013)