The preparation of 2,4-dibromoestra-1,3,5(10),6-tetraene-3,17 β-diol diacetate

Article abstract of DOI:10.1016/0039-128X(91)90072-4

[2,4,6,7-³H₄]Estradiol is used for the quantitative determination of estradiol receptors. The synthesis of 2,4-dibromoestra-1,3,5(10),6-tetraene-3,17β-diol 3,17-diacetate, the convenient precursor of [2,4,6,7-³ H₄]estradiol, is described. 6-Alkoxy compounds were also prepared and investigated.