
Journal of the Chemical Society. Perkin transactions I p. 3137 - 3144 (1990)
Update date:2022-08-04
Topics:
Fraser, William
Suckling, Colin J.
Wood, Hamish C. S.
A series of 5-spirocyclopropanobarbiturates bearing alkyl and aryl substituents on the cyclopropane ring has been synthesized.Dihydro-orotate dehydrogenase from Clostridium oroticum was shown to be inhibited by these compounds.A related series of 5-member
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Doi:10.3987/COM-90-5493
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