Syntheses and antifungal activity of dl-griseofulvin and its congeners. II

DOI: 10.1248/cpb.45.327

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 327 - 332 (1997)

Update date:2022-07-29

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Authors:

Takeuchi, Yasuo

Tomozane, Hideo

Misumi, Keiji

Yata, Kuniko

Kawata, Teruyuki

Niino, Yoshiko

Yamato, Masatoshi

Harayama, Takashi

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Article abstract of DOI:10.1248/cpb.45.327

Griseofulvin derivatives, dl-6'-demethyl-6'-ethylgriseofulvin (dl-5) and dl-6'-demethyl-6'-phenylgriseofulvin (dl-6) were prepared by application of a synthetic method developed by us. Antifungal activity of these derivatives decreased in the order of dl-

Full text of DOI:10.1248/cpb.45.327

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