SYNTHESIS OF HETEROCYCLES ON THE BASIS OF PRODUCTS OF ADDITION OF POLYHALOALKANES TO UNSATURATED SYSTEMS. 2. OBTAINING ISOXAZOLE DERIVATIVES BY 1,3-DIPOLAR CYCLOADDITION WITH THE PARTICIPATION OF POLYHALO-SUBSTITUTED ALKENECARONITRILE OXIDES

Article abstract of DOI:10.1007/BF00472490

Oximes of 3,3-dichloropropenal and 4,4,4-trifluoro-3-chloro-1-butenal were obtained on the basis of products of free-radical addition of CCl4 and CF3CCl3 to vinyl butyl ether.Generation of the corresponding nitrile oxides from these oximes and reaction of the nitrile oxides in situ with vinyl butyl ether, phenylacetylene, and propargyl alcohol via the scheme of 1,3-dipolar cycloaddition are proposed as a method for the synthesis of isoxazoles containing β,β-dichlorovinyl and β-trifluoromethyl-β-chlorovinyl substituents in the 3 position.