Journal of the Chemical Society. Chemical communications p. 11 - 12 (1995)
Update date:2022-09-26
Topics:
Chung, Sung-Kee
Chang, Young-Tae
Synthesis of all possible nine regioisomers of IP4, some of which are implicated as second messengers in the cellular signalling, was accomplished from myo-inositol via its dibenzoate derivatives (IBz2) as the key intermediates; base-catalysed isomerization of readily available I(1,4)Bz2 and its derivatives, followed by suitable separation procedures efficiently provided all nine regioisomers of IBz2.
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