Synthesis of 4-deoxy and 4-deoxy-4-halogeno derivatives of L-fucose as potential enzyme inhibitors

Article abstract of DOI:10.1016/0008-6215(91)80150-L

Methyl-2,3-di-O-benzoyl-6-deoxy-α-L-galactopyranoside (2) was converted into the 4-deoxy-4-iodo-α-L-gluco derivative 4 by triflate-mediated inversion.Catalytic reduction of 4 gave methyl 2,3-di-O-benzoyl-4,6-dideoxy-α-L-xylo-hexopyranoside (6) and subsequ