Total synthesis of the esterase inhibitor (±)-ebelactone A using an aldol-Claisen strategy

DOI: 10.1016/S0040-4039(00)88532-9

Source and publish data:

Tetrahedron Letters p. 7513 - 7516 (1990)

Update date:2022-08-03

Topics:

Authors:

Paterson

Hulme Hulme

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)88532-9

The β-lactones (±)-ebelactone A has been prepared in 12 steps from diethylketone (9% overall yield) using a series of three boron enolate aldol reactions coupled with the Ireland ester enolate Claisen rearrangement, 10→11.

Full text of DOI:10.1016/S0040-4039(00)88532-9

Products guided by the article

Product name:(+/-)-Ebelactone A

Cas No:133006-99-2

R&D Labs maybe for 133006-99-2

Jiangxi Biochem Co.,Ltd

Contact:86-791-86629460

Address:1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Suzhou HeChuang Chemical Co.,Ltd.

Contact:+86-512-88800520

Address:No.9 Guanchao Rd,Changshu Advanced Materials Industy Park
Jiangxi Dongxu Chemical Science & Technology Co.,Ltd

Contact:+86-791-86899381

Address:Nanchang, Jiangxi, China
Nanjing Yuance Industry&Trade Co., Ltd.

website:http://www.njyuance.cn/

Contact:+86-25-85439097

Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China

Relevant to this article

Organocatalytic, oxidative, intermolecular amination and hydrazination of simple arenes at ambient temperature

Doi:10.1021/ol302607y
(2012)
Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours

Doi:10.1016/j.bmcl.2017.03.027
(2017)
Newly synthesized bis-benzimidazole derivatives exerting anti-tumor activity through induction of apoptosis and autophagy

Doi:10.1016/j.bmcl.2012.06.102
(2012)
Pd/Ni-Catalyzed Germa-Suzuki coupling via dual Ge-F bond activation

Doi:10.1039/d1cc01392k
(2021)
Characterization of DMSO coordination to palladium(II) in solution and insights into the aerobic oxidation catalyst, Pd(DMSO)₂(TFA) ₂

Doi:10.1021/ic301799p
(2012)
AgONO-Assisted Direct C-H Arylation of Heteroarenes with Anilines

Doi:10.1002/chem.201403640
(2014)

Article Doi