A novel synthesis of α-aminoaldehydes from glyoxal monoacetal

DOI: 10.1055/s-1990-27128

Source and publish data:

Synthesis p. 1173 - 1176 (1990)

Update date:2022-08-03

Topics:

Authors:

Katritzky

Borowiecka

Fan Fan

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1990-27128

Primary and secondary amines condense with benzotriazole and glyoxal monoacetal to give N-substituted 1-(benzotriazolyl)-2,2-diethoxyethylamines 4, which with Grignard reagents readily yield the corresponding 2-aminoalkanal diethylacetal 5. These are easily hydrolyzed to produce α-aminoaldehydes 6.

Full text of DOI:10.1055/s-1990-27128

Products guided by the article

Product name:1-(benzotriazolyl)-N,N-dibenzyl-2,2-diethoxyethylamine

Cas No:132870-09-8

R&D Labs maybe for 132870-09-8

Tianjin Boron PharmaTech Co.,Ltd.(expird)

Contact:86-022-59845187

Address:B9-401, Tianda Science Park,No.80,4th Avenue,TEDA,Tianjin, China
enantiotech corporation ltd

Contact:+86-0760-85282375

Address:zhongjing road,zhongshan torch hi-tech industrial development zone
GN chemicals co.,ltd

Contact:86 311 85902108 / 85902109

Address:room 1001-1005 ,huanghe Road ,shijiazhuang ,China
Wuxi Morality Chemical Co., Ltd(expird)

Contact:

Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
Shanghai Yuking Water Soluble Material Tech Co., Ltd

Contact:86-21-68286299

Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China

Relevant to this article

Preparation of 2-Hydroxy-1,2-Diphenylethyl Phenylphosphinate: a Chiral Reagent for Asymmetric Reduction of Ketones

Doi:10.1016/S0957-4166(00)82386-1
(1990)
Diastereomeric resolution of rac -1,1′-bi-2-naphthol boronic acid with a chiral boron ligand and its application to simultaneous synthesis of (R)- and (S)-3,3′-disubstituted 1,1′-bi-2-naphthol derivatives

Doi:10.1021/jo400928q
(2013)
Generation and Spectroscopic Characterization of the First Chloro(2,4,6-tri-t-butylphenylimino)phosphine Complexes

Doi:10.1039/c39910000041
(1991)
Combining Photo-Organo Redox- and Enzyme Catalysis Facilitates Asymmetric C-H Bond Functionalization

Doi:10.1002/ejoc.201801692
(2019)
Spectral, magnetic, thermal, molecular modelling, ESR studies and antimicrobial activity of (E)-3-(2-(2-hydroxybenzylidene) hydrazinyl)-3-oxo- n(thiazole-2-yl)propanamide complexes

Doi:10.1016/j.molstruc.2011.06.050
(2011)
An unexpected result from the reaction of hydroxymethyl-2-oxazolidinones with isocyanates

Doi:10.1007/s10593-011-0741-0
(2011)

Article Doi