New nonpeptide angiotensin II receptor antagonists. 1. Synthesis, biological properties, and structure-activity relationships of 2-alkyl benzimidazole derivatives

DOI: 10.1021/jm00083a011

Source and publish data:

Journal of Medicinal Chemistry p. 877 - 885 (1992)

Update date:2022-08-04

Topics:

Authors:

Thomas Thomas

Allott Allott

Gibson Gibson

Major Major

Masek Masek

Oldham Oldham

Ratcliffe

Roberts Roberts

Russell Russell

Thomason

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Article abstract of DOI:10.1021/jm00083a011

On the basis of an extension of the literature lead 1, a series of benzimidazoles have been synthesized and shown to be angiotensin II (AII) receptor antagonists. The structure-activity relationships of these new antagonists have been explored and the key

Full text of DOI:10.1021/jm00083a011

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