PREPARATION OF 1-BENZOYL-4-(AMINO)-1,2,2a,3,4,5-HEXAHYDROBENZINDOLES FROM L-TRYPTOPHAN

Article abstract of DOI:10.1016/S0040-4039(00)97304-0

Acid 6a, derived from L-tryptophan, has been shown to be a useful precursor to partial ergot structures such as 3.Optically pure amine (+)-13, a key intermediate in the synthesis of 3, was prepared in 45percent overall yield from 6a via a four step sequen