Journal of Medicinal Chemistry p. 1818 - 1822 (1991)
Update date:2022-08-04
Topics: Antimalarials Flavins
Cowden
Halladay
Cunningham
Hunt
Clark
A series of 3-methyl-10-(substituted-phenyl)flavins was prepared and tested for antimalarial activity against the lethal parasite Plasmodium vinckei in mice. Several of these analogues were found to be effective antimalarial agents. A quantitative structure-activity relationship study was undertaken with 44 analogues and no satisfactory relationship could be established.
View MoreBeijing Mesochem Technology Co.,LTD
website:http://www.mesochem.com
Contact:0086-10-57862036
Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
shanghai hekang chemical co.ltd
Contact:021-54173790
Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
Taizhou Elitechemie MediPharma Technology Co.,Ltd.
Contact:+86-523-86810021
Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
Shanghai Hohance Chemical Co., ltd
Contact:13914753421
Address:Fl.5；Bld. 70, Lane 1500; Xinfei Road
shandong zhongke taidou chemical co.,ltd
Contact:86-531-88682301
Address:Jinan shandong Province CHina
Doi:10.1002/chem.201101300
(2011)Doi:10.1002/anie.201103360
(2011)Doi:10.1016/j.bmcl.2017.08.022
(2017)Doi:10.1021/jacs.5b11892
(2016)Doi:10.1007/BF00472482
(1990)Doi:10.1007/BF00476974
(1990)
