Synthesis and antidopaminergic activity of some 3-(aminomethyl)tetralones as analogues of butyrophenone

DOI: 10.1021/jm00111a046

Source and publish data:

Journal of Medicinal Chemistry p. 2242 - 2247 (1991)

Update date:2022-08-04

Topics:

Authors:

Cortizo Cortizo

Santana Santana

Ravina Ravina

Orallo Orallo

Fontenla

Castro Castro

Calleja Calleja

De Ceballos

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Article abstract of DOI:10.1021/jm00111a046

Starting from β-benzoylpropionic acid we synthesized 3-(aminomethyl)tetralones in which the amino substituent was 4-(N-piperazinyl)-p-fluorobutyrophenone (14), 4-benzoylpiperidine (15), 4-hydroxy-4-phenylpiperidine (16) or 4-(o-methoxyphenyl)piperazine (1

Full text of DOI:10.1021/jm00111a046

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