One-step synthesis of 1,n-dicarbonyl compounds from carboxylic acid derivatives and di-Grignard reagents in the presence of transition metal catalysts

Article abstract of DOI:10.1016/0022-328X(91)83155-W

The transition metal catalyzed cross-coupling reaction of alkane di-Grignard reagents with carboxylic acid derivatives provides a convenient one-step synthesis of symmetrical 1,n-diketones (n<*>8) and long-chain dicarboxylic thiol esters.