Chiral aminal templates: Diastereoselective addition to hydrazones; an asymmetric synthesis of α-amino aldehydes

DOI: 10.1055/s-1995-4042

Source and publish data:

Synthesis p. 1038 - 1050 (1995)

Update date:2022-07-29

Topics: Asymmetric synthesis α-amino aldehydes

Authors:

Alexakis

Lensen Lensen

Tranchier

Mangeney

Feneau-Dupont

Declercq

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1995-4042

The monohydrazone of glyoxal may be derivatized into a chiral aminal with diamine 7. The resulting chiral reagent 13 reacts with complete diastereocontrol with organolithium reagents in THF. This sterically controlled reaction may be altered to chelation

Full text of DOI:10.1055/s-1995-4042

Products guided by the article

Product name:(4S,5S)-2-<(S)-1-(N,N-dimethylhydrazino)-3-methylbut-2-enyl>-1,3-dimethyl-4,5-diphenylimidazolidine

Cas No:133643-30-8

R&D Labs maybe for 133643-30-8

Hebei DaPeng Pharm & Chem Co., Ltd.

Contact:86-317-7298678,0576-88861898 88861908

Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
Zhengzhou Xinlian Chemical Tech Co. ,Ltd

Contact:0371-65771781 021-52042910

Address:H Part, Building I, No. 700 Gonglu Road, Pudong New Area, Shanghai
Changzhou Litong Chemical Co., Ltd.

website:http://www.litonchem.com/

Contact:+86-519-86301238

Address:Laoba Rd, Hutang town Changzhou Jiangsu
EnBridge PharmTech Co., Ltd.

website:http://www.enbridgepharm.com

Contact:+86-510-83591909

Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
Zhejiang Sanmei Chemical Industry Co., Ltd

Contact:86-579-87633213

Address:Huchu Industrial Zone, Qingnian Rd., Wuyi County, Zhejiang Prov., China.

Relevant to this article

A C-H functionalization protocol for the direct synthesis of benzobisthiazole derivatives

Doi:10.1021/jo501416j
(2014)
Synthesis Utilizing Reducing Ability of Carbon Monoxide: A New Method for Selective Synthesis of Diorganyl Selenides and Diselenides Using a Selenium-Carbon Monoxide-Water Reaction System

Doi:10.1021/jo00012a006
(1991)
Odorless eco-friendly synthesis of thio- and selenoglycosides in ionic liquid

Doi:10.1055/s-0030-1260966
(2011)
Effects of central metal ions on vibrational circular dichroism spectra of tris-(β-diketonato)metal(III) complexes

Doi:10.1021/ic070300i
(2007)
Direct access to β-oxodiazo compounds by copper(II)-catalyzed oxidative rearrangement of stabilized vinyl diazo derivatives

Doi:10.1021/ja208965b
(2011)
Difluoromethylation of Alkenes via Borohydride Reduction of 1,3-Dibromo-1,1-difluoroalkanes

Doi:10.1021/jo00013a051
(1991)

Article Doi