Synthesis and antiviral and cytostatic properties of 3'-deoxy-3'-fluoro- and 2'-azido-3'-fluoro-2',3'-dideoxy-D-ribofuranosides of natural heterocyclic bases

DOI: 10.1021/jm00111a040

Source and publish data:

Journal of Medicinal Chemistry p. 2195 - 2202 (1991)

Update date:2022-08-02

Topics:

Authors:

Mikhailopulo

Poopeiko

Pricota Pricota

Sivets Sivets

Kvasyuk Kvasyuk

Balzarini

De Clercq

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00111a040

A series of 3'-deoxy-3'-fluoro- and 2'-azido-2',3'-dideoxy-3'-fluoro-D-ribofuranosides of natural heterocyclic bases have been synthesized with the use of universal carbohydrate precursors, viz., 1-O-acetyl-2,5-di-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose

Full text of DOI:10.1021/jm00111a040

Products guided by the article

Product name:Benzoic acid (2R,3S,4S,5S)-4-azido-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3-fluoro-tetrahydro-furan-2-ylmethyl ester

Cas No:133776-19-9

R&D Labs maybe for 133776-19-9

Shanghai birch chemical technology co.,ltd

Contact:+86-21-54096810

Address:No.2588,Jungong Road,Shanghai,China
Beijing Top Science biological technology co., LTD

Contact:+86-13439059536

Address:15-1705 jre three mile, Beijing 100000,CHINA
Zhejiang Hoshine Silicon Industry Co., Ltd.

Contact:86-573-89179966

Address:Zhapu Town, Pinghu City, Zhejiang, China
Chengdu D-Innovation Pharmaceutical Co., Ltd

Contact:86-28-85105536

Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
Ji'an Hairui Natural Plant Co. Ltd.

Contact:0796-8105528

Address:Meilin industry park, Qingyuan district Ji'an City, Jiangxi Province

Relevant to this article

Binaphthol-catalyzed asymmetric conjugate arylboration of enones

Doi:10.1021/ol202391r
(2011)
Synthesis of 2 H-indazoles by the [3 + 2] dipolar cycloaddition of sydnones with arynes

Doi:10.1021/jo201605v
(2011)
Unichiral 2-(2′-pyrrolidinyl)-1,4-benzodioxanes: The 2 R,2′ S diastereomer of the N -methyl-7-hydroxy analogue is a potent α4β2- and α6β2-nicotinic acetylcholine receptor partial agonist

Doi:10.1021/jm200937t
(2011)
Improvement in potency of an oxytocin antagonist after systematic substitutions with L-tryptophan

Doi:10.1021/jm00111a025
(1991)
Design and Identification of a Novel, Functionally Subtype Selective GABA_A Positive Allosteric Modulator (PF-06372865)

Doi:10.1021/acs.jmedchem.9b00322
(2019)
SAR studies of acidic dual γ-secretase/PPARγ modulators

Doi:10.1016/j.bmc.2011.08.003
(2011)

Article Doi