Synthesis and anticonvulsant activity of new 1-[2-oxo-2-(4-phenylpiperazin- 1-yl)ethyl]pyrrolidine-2,5-diones

DOI: 10.1016/j.bmcl.2011.07.118

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 5800 - 5803 (2011)

Update date:2022-08-04

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Authors:

Kamiński, Krzysztof

Rzepka, Sabina

Obniska, Jolanta

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Article abstract of DOI:10.1016/j.bmcl.2011.07.118

Twenty-two new 1-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5- diones were synthesized and tested for anticonvulsant activity. Initial anticonvulsant screening was performed using standard maximal electroshock (MES) and subcutaneous pentylenetet

Full text of DOI:10.1016/j.bmcl.2011.07.118

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