Purine and 1-Deazapurine Ribonucleosides and Deoxyribonucleosides: Synthesis and Biological Activity

DOI: 10.1021/jm00111a044

Source and publish data:

Journal of Medicinal Chemistry p. 2226 - 2230 (1991)

Update date:2022-08-03

Topics:

Authors:

Cristalli, Gloria

Vittori, Sauro

Eleuteri, Alessandra

Grifantini, Mario

Volpini, Rosaria

et al. et al.

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Article abstract of DOI:10.1021/jm00111a044

A series of 6-(hydroxylamino)purine and -1-deazapurine nucleosides were synthesized and tested for their antitumor and adenosine deaminase inhibitory activity.All the examined molecules displayed an in vitro activity comparable to that of the reference co

Full text of DOI:10.1021/jm00111a044

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