Journal of Medicinal Chemistry p. 2268 - 2274 (1991)
Update date:2022-08-03
Topics:
Hodgkiss
Jones
Long
Middleton
Parrick
Stratford
Wardman
Wilson
Several novel compounds having both a 2-nitroimidazole nucleus and a fluorescent ring system in their molecular structure were prepared and evaluated as potential fluorescent probes for hypoxia. Bioreduction of nitroimidazoles, which is inhibited by oxyge
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