Hypersensitive acid-labile (HAL) tris(alkoxy)benzyl ester anchoring for solid-phase synthesis of protected peptide segments

DOI: 10.1016/S0040-4039(00)74475-3

Source and publish data:

Tetrahedron Letters p. 1015 - 1018 (1991)

Update date:2022-07-29

Topics:

Authors:

Albericio

Barany Barany

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Article abstract of DOI:10.1016/S0040-4039(00)74475-3

The novel 5-(4-hydroxymethyl-3,5-dimethoxyphenoxy)valeric acid (HAL) handle has been prepared and applied to solid-phase peptide synthesis using 9-fluorenylmethyloxycarbonyl(Fmoc) for N(α)-amino protection and tert-butyl ethers, esters, and urethanes for

Full text of DOI:10.1016/S0040-4039(00)74475-3

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Product name:5-(4-Hydroxymethyl-3,5-dimethoxy-phenoxy)-pentanoic acid

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