A VERSATILE SOLID PHASE METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDE-3'-PHOSPHATES

DOI: 10.1016/S0040-4039(00)92132-4

Source and publish data:

Tetrahedron Letters p. 967 - 970 (1991)

Update date:2022-08-03

Topics:

Authors:

Kumar, Pradeep

Bose, N. K.

Gupta, K. C.

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Article abstract of DOI:10.1016/S0040-4039(00)92132-4

The polymer support 6 with 4,4'-dimethoxytrityloxy-2-mercaptoethyl group allows the automated oligonucleotide synthesis giving rise to oligonucleotide-3'-phosphate during final deprotection with ammonical DTT at 55 deg C.

Full text of DOI:10.1016/S0040-4039(00)92132-4

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