Acid-promoted reaction of cyclic allylic diols with carbonyl compounds. Stereoselective ring-enlarging tetrahydrofuran annulations

Article abstract of DOI:10.1021/ja00014a031

A wide variety of cis-fused hexahydrocyclopenta[b]furan-4-ones (3, n = 0), hexahydro-4(2H)-benzofuranones (3, n = 1), and octahydrocyclohepta[b]furan-4-ones (3, n = 2) can be prepared with high levels of stereocontrol by the title reaction. The scope and