Optical resolution of N-carbobenzoxy-α-methoxyglycine

Article abstract of DOI:10.1016/S0957-4166(00)86033-4

Optical resolution of racemic N-carbobenzoxy-α-methoxyglycine using D/L-phenylalaninol or (1S,2S)-2-amino-1-phenyl-1,3-propanediol afforded (+)- and (-)-enantiomers, to which D- and L-configurations, respectively, were assigned based on the ¹H NMR data and biological activity of dermorphin N-terminal tetrapeptide analogs.