Highly stereoselective preparation of conjugated dienones and dienoates via a new knvnagel approach

Article abstract of DOI:10.1016/S0040-4039(00)74331-0

2E,4E α,β:γ,δ dienones and dienoates were prepared in good to excellent yields by the condensation of unsaturated aldehydes with ketone and ester lithium enolates in the presence of trimethylchlorosilane. Application of this process to cis olefinic aldehydes provides a new route to 2E,4Z-dienones.