An efficient synthesis of enantiomerically pure trans-2-phenylcyclohexanol

DOI: 10.1016/S0040-4039(00)77259-5

Source and publish data:

Tetrahedron Letters p. 5611 - 5612 (1994)

Update date:2022-07-29

Topics:

Authors:

King, S. Bruce

Sharpless, K. Barry

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Article abstract of DOI:10.1016/S0040-4039(00)77259-5

Both enantiomers of trans-2-phenylcyclohexanol (3), Whitesell's auxiliary, have been prepared in a simple two step sequence featuring a catalytic asymmetric dihydroxylation followed by stereo selective hydrogenolysis.

Full text of DOI:10.1016/S0040-4039(00)77259-5

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