The Dolastatins 20. Convenient Synthetic Route to Dolastatin 15

DOI: 10.1016/S0040-4020(01)89562-4

Source and publish data:

Tetrahedron p. 12097 - 12108 (1994)

Update date:2022-08-03

Topics: Synthetic route Experimental Chemical terms

Authors:

Pettit, George R.

Thornton, Timothy J.

Mullaney, Jeffrey T.

Boyd, Michael R.

Herald, Delbert L.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)89562-4

A segment synthetic strategy was utilized for obtaining the Dolabella auricularia (Indian Ocean sea hare) depsipeptide dolastatin 15.Reaction of protected (S)-Hiva-(S)-Phe 2c with isopropenyl chloroformate followed by Meldrum's ester, cyclization (2c -> 3

Full text of DOI:10.1016/S0040-4020(01)89562-4

Products guided by the article

Product name:(S)-Hiva-(S)-Phe-OMe

Cas No:134816-19-6

R&D Labs maybe for 134816-19-6

TAIZHOU XINGCHENG CHEMPHARM CO.,LTD.

Contact:0086-0576-88551200,88886292 ,88880039

Address:B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China
Hangzhou Dingyan Chem Co., Ltd

website:http://www.dingyanchem.com

Contact:86-571-87157530

Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004
Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang
Wansheng

Contact:86-21-31200601

Address:Room1618,FangzhengDaSha,No.1122 Xinjinqiao Road,Pudong New District,Shanghai ,China
zhenjiang runjing high purity chemical co ltd

Contact:+86-511-83361155

Address:No.8.haixi road,international chemical park

Relevant to this article

Oxidation of alkyl and aryl iodides, phenylacetaldehyde and alkenes by dimethyldioxirane. Reaction products and mechanism

Doi:10.1016/00404-0399(50)1376S-
(1995)
A single-component liquid-phase hydrogen storage material

Doi:10.1021/ja208834v
(2011)
Ir(I)-catalyzed enantioselective secondary sp³ C-H bond activation of 2-(alkylamino)pyridines with alkenes

Doi:10.1021/ol201907w
(2011)
Diastereo- and enantioselective catalytic vinylogous mukaiyama-mannich reactions of pyrrole-based silyl dienolates with alkyl-substituted aldehydes

Doi:10.1021/jo201875a
(2011)
First nucleophilic addition of acetylide to 1,3-diketonate anions: Reaction of 1-aryl-4,4,4-trifluorobutane-1,3-diones with sodium acetylide

Doi:10.1016/j.tetlet.2011.09.153
(2011)
Efficient Synthesis of 5-Trifluoromethylthio-1,2,3-Triazoles: One-Pot Multicomponent Reaction from Elemental Sulfur and TMSCF 3

Doi:10.1055/s-0039-1690716
(2020)

Article Doi