The synthesis and antiviral activity of some 4'-thio-2'-deoxy nucleoside analogues

DOI: 10.1021/jm00113a016

Source and publish data:

Journal of Medicinal Chemistry p. 2782 - 2786 (1991)

Update date:2022-08-03

Topics:

Authors:

Dyson Dyson

Coe Coe

Walker Walker

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Article abstract of DOI:10.1021/jm00113a016

Starting from benzyl 3,5-di-O-benzyl-2-deoxy-1,4-dithio-D-erythro-pentofuranoside (4), the following 2'-deoxy nucleoside analogues have been synthesized: 4'-thiothymidine (8), 3'-azido-4'-thio-deoxythymidine (10), and (E)-5-(2-bromovinyl)-4'-thio-2'-deoxy

Full text of DOI:10.1021/jm00113a016

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