Synthesis of β-(Trifluoromethyl)pyrroles via the Cycloaddition of Munchnones to Electron-Deficient Trifluoromethylated Olefins

DOI: 10.1021/jo00018a011

Source and publish data:

Journal of Organic Chemistry p. 5259 - 5262 (1991)

Update date:2022-08-05

Topics:

Authors:

Okano, Takashi

Uekawa, Toru

Morishima, Norihito

Eguchi, Shoji

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00018a011

The 1,3-dipolar cycloaddition of munchnones (1,3-oxazolium 5-olates) to β-chloro-β-(trifluoromethyl)vinyl phenyl ketone (1) and butyl β-chloro-γ,γ,γ-trifluorocrotonate (2) gave (trifluoromethyl)pyrroles.The monocyclic munchnones 3a-c yielded the β-(triflu

Full text of DOI:10.1021/jo00018a011

Products guided by the article

Product name:butyl 3-phenyl-2-(trifluoromethyl)-5,10-dihydropyrrolo<1,2-b>isoquinoline-1-carboxylate

Cas No:135106-31-9

R&D Labs maybe for 135106-31-9

Nanjing Legend Pharmaceutical & Chemical Co., Ltd.

Contact:+86-25-83767696

Address:14-7 Zhongshan Lu Guluo District, Nanjing
Tosta Enterprise Co., Ltd.

Contact:+86-134-5286-9121

Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Changsha Nutritopper Bio Technology Co.,Ltd.

Contact:+86-731-87803543

Address:East 1st Street, Baima Road, Ningxiang County
Shanghai Kangxin Chemical Co., Ltd

Contact:+86 21 60717227

Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai
Chongqing Shuangfeng Chemical Co.,Ltd

Contact:+86-23-49850156

Address:No.663,xuanhua Rd,yongchuan,chongqing,China

Relevant to this article

Dual inhibitors of P-glycoprotein and tumor cell growth: (Re)discovering thioxanthones

Doi:10.1016/j.bcp.2011.10.004
(2012)
Molecular iodine-catalyzed one-pot synthesis of tetrahydrobenzo[a]xanthene- 11-one and diazabenzo[a]anthracene-9,11-dione derivatives

Doi:10.1080/00397911.2010.541966
(2012)
AMINOMETHYLATION OF 1-R-TETRAZOLES

Doi:10.1007/BF00633218
(1991)
Synthesis of 2-deoxy-2-[(3R)-3-hydroxytetradecanamido]-3-O-[(3R)-3-hydroxytetradecan yl]-α-D-glucopyranosyl dihydrogen phosphate and 2-deoxy-2-[(3R)-3-hydroxy-tetradecanamido]-3-O-[(3R)-3-hydoxytetradecan yl]-4-O-phosphono-D-glucopyranose

Doi:10.1016/0008-6215(91)89006-2
(1991)
Tetra- and hexadentate Schiff base ligands and their Ni(II), Cu(II) and Zn(II) complexes. Synthesis, spectral, magnetic and thermal studies

Doi:10.1016/j.saa.2011.10.037
(2012)
Metal-free directed ortho C-H iodination: Synthesis of 2'-iodobiaryl-2- carbonitriles

Doi:10.1002/ejoc.201300584
(2013)

Article Doi