Journal of Medicinal Chemistry p. 8473 - 8494 (2016)
Update date:2022-08-03
Topics:
Cioffi, Christopher L.
Liu, Shuang
Wolf, Mark A.
Guzzo, Peter R.
Sadalapure, Kashinath
Parthasarathy, Visweswaran
Loong, David T. J.
Maeng, Jun-Ho
Carulli, Edmund
Fang, Xiao
Karunakaran, Kalesh
Matta, Lakshman
Choo, Sok Hui
Panduga, Shailijia
Buckle, Ronald N.
Davis, Randall N.
Sakwa, Samuel A.
Gupta, Priya
Sargent, Bruce J.
Moore, Nicholas A.
Luche, Michele M.
Carr, Grant J.
Khmelnitsky, Yuri L.
Ismail, Jiffry
Chung, Mark
Bai, Mei
Leong, Wei Yee
Sachdev, Nidhi
Swaminathan, Srividya
Mhyre, Andrew J.
We previously disclosed the discovery of rationally designed N-((1-(4-(propylsulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide inhibitors of glycine transporter-1 (GlyT-1), represented by analogues 10 and 11. We describe herein further structure-activit
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