Asymmetric Synthesis of 2-Alkyl(Aryl)-2,3-dihydro-4-pyridones by Addition of Grignard Reagents to Chiral 1-Acyl-4-methoxypyridinium Salts

DOI: 10.1021/jo00296a006

Source and publish data:

Journal of Organic Chemistry p. 2574 - 2576 (1990)

Update date:2022-09-26

Topics:

Authors:

Comins, Daniel L.

Goehring, R. Richard

Joseph, Sajan P.

O'Connor, Sean

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00296a006

Grignard addition to a chiral 1-acyl-4-methoxypyridinium salt provides synthetically useful 2-alkyl(aryl)-2,3-dihydro-4-pyridones in high diastereomeric excess.

Full text of DOI:10.1021/jo00296a006

Products guided by the article

Product name:1-((1S,2R,5S)-2-Isopropyl-5-methyl-cyclohexyloxycarbonyl)-4-methoxy-3-triisopropylsilanyl-pyridinium; chloride

Cas No:135365-65-0

R&D Labs maybe for 135365-65-0

Yueyang Hudex Pharmaceuticals Ltd.

Contact:0730-8748800

Address:Wujiang Bridge，Yueyang Economy & Technology Development Zone
Hisyntech Corporation Limited

Contact:0086-22-23410962

Address:17-201, Ningfuli, Shuishanggongyuandong road,Nankai district, Tianjin, China
JinTan Pingsheng Chemical Co.,Ltd

Contact:+86-519-82828200

Address:NO.11Danfengxilu Road,Jintan City,Jiangsu,China
Yantai Derun Liquid Crystal Materials Co. Ltd.

website:http://www.ytderun.com

Contact:86-535-6300169

Address:ROOM 90, XIANGFU STREET, FUSHAN NEW-HIGH-TECH IDUSTRY ZONE, YANTAI
Shandong Dayi Chemical Co., Ltd.

website:http://www.dayi.com.cn

Contact:+86- 535-7388728. 15306386031

Address:No 1 Danya west road, Laiyang City, Shandong province

Relevant to this article

Metal-free dihydroxylation of alkenes using cyclobutane malonoyl peroxide

Doi:10.1021/jo202084w
(2012)
Synthesis and evaluation of structural requirements for antifungal activity of cyrmenin B₁ analogues

Doi:10.1016/j.tetlet.2011.11.023
(2012)
Surprising repair activities of nonpolar analogs of 8-oxoG expose features of recognition and catalysis by base excision repair glycosylases

Doi:10.1021/ja208510m
(2012)
Synthesis and characterization of new derivatives of 1,4-diazepinium salts

Doi:10.1080/00397911.2010.518332
(2011)
Doi:10.1021/ja00752a075
(1971)
Ruthenium-catalyzed oxidative C - H alkenylations of anilides and benzamides in water

Doi:10.1021/ol203251s
(2012)

Article Doi