Mechanistic Aspects of the Oxidation of 1,3-Disubstituted 6-Amino-5-nitrosouracils with Lead Tetraacetate: The Formation of Pyrimidopteridinetetrone 10-Oxides

Article abstract of DOI:10.1021/jo00022a017

Lead tetraacetate oxidation of 1,3-disubstituted 6-amino-5-nitrosouracils 1 in glacial acetic acid results in the formation of 1,3,6,8-tetrasubstituted pyrimido<5,4-g>pteridine-2,4,5,7(1H,3H,6H,8H)-tetrone 10-oxides 2.ESR studies and a number of chemical