Journal of Organic Chemistry p. 5610 - 5614 (1991)
Update date:2022-07-30
Topics:
Strekowski, Lucjan
Wydra, Roman L.
Janda, Lubomir
Harden, Donald B.
4,5-Dimethyl- and 4,5,6-trimethyl-substituted pyrimidines are brominated at C5-Me with NBS in CCl4 and at C4(6)-Me with bromine in acetic acid to give the corresponding bromomethyl derivatives in a high yield.The remaining methyl group(s) can also be brominated with high regioselectivity.The 2-methylthio substituent is not oxidized under these conditions.
View MoreJIANGXI XINXIN CHEMICAL CO., LTD.
Contact:86-15957176628
Address:INDUSTRY ROAD 1, INDUSTRIAL PARK, HEKOU TOWN,YANSHAN COUNTY, JIANGXI PROVINCE, CHINA
Shijiazhuang Haitian Amino Acid Co., Ltd.
Contact:+86-311-88908111
Address:Shijiazhuang Hebei province,China
Hangzhou J&H Chemical Co., Ltd.
website:http://www.jhechem.com/
Contact:+86-571-87396432
Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China
Huaian Double Win Chemicals Co.,Ltd.
Contact:+86-13511538872
Address:Blk 43,Greenland Century Town,Huaian District, Huaian City,Jiangsu Province,China
website:http://www.chinacharm.cn/
Contact:86 551 5316260
Address:No. 211,XiangZhang Road,Hefei City,Anhui Province,China
Doi:10.1002/cbic.201800170
(2018)Doi:10.1021/ja209335z
(2012)Doi:10.1039/c9nj02672j
(2019)Doi:10.1002/ejoc.201101364
(2012)Doi:10.1002/ejoc.201101028
(2012)Doi:10.1016/j.bmcl.2011.12.021
(2012)
