Organocatalytic asymmetric synthesis of 3-difluoroalkyl 3-hydroxyoxindoles

DOI: 10.1039/c2cc17140f

Source and publish data:

Chemical Communications p. 1919 - 1921 (2012)

Update date:2022-07-30

Topics:

Authors:

Liu, Yun-Lin

Zhou, Jian

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Article abstract of DOI:10.1039/c2cc17140f

We report the first example of highly enantioselective organocatalytic synthesis of 3-difluoroalkyl substituted 3-hydroxyoxindoles. The total synthesis of the difluoro analogue of convolutamydine E was achieved by this method.

Full text of DOI:10.1039/c2cc17140f

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