ISOLATION OF DIHYDROCLAVAMINIC ACID, AN INTERMEDIATE IN THE BIOSYNTHESIS OF CLAVULANIC ACID

DOI: 10.1016/S0040-4020(01)86446-2

Source and publish data:

Tetrahedron p. 4089 - 4100 (1991)

Update date:2022-09-26

Topics: Isolation Clavulanic acid Biosynthesis Chemical compound Enzymatic pathways

Authors:

Baldwin, Jack E.

Adlington, Robert M.

Bryans, Justin S.

Bringhen, Alain O.

Coates, Janice B.

et al. et al.

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Article abstract of DOI:10.1016/S0040-4020(01)86446-2

A primary isotope effect was utilised in an in vitro study to allow the isolation and characterisation of an intermediate between proclavaminic acid and clavaminic acid, in clavulanic acid biosynthesis.

Full text of DOI:10.1016/S0040-4020(01)86446-2

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