Isopenicillin N Synthase: A New Mode of Reactivity

DOI: 10.1039/c39910000736

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 736 - 738 (1991)

Update date:2022-09-26

Topics:

Authors:

Baldwin, Jack E.

Lynch, Gregory P.

Schofield, Christopher J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39910000736

Incubation of δ-(L-α-aminoadipoyl)-L-(3,3-difluorohomocysteinyl)-D-valine with isopenicillin N synthase gave a thiocarboxylic acid, consistent with the formation of a monocyclic lactam intermediate.

Full text of DOI:10.1039/c39910000736

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:(4R)-1-benzyl-3,3-difluoro-4-<(1'R)-1',2'-dihydroxyethyl>azetidin-2-one

Cas No:135777-61-6

R&D Labs maybe for 135777-61-6

jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china
JinTan Pingsheng Chemical Co.,Ltd

Contact:+86-519-82828200

Address:NO.11Danfengxilu Road,Jintan City,Jiangsu,China
ANHUI WEICHI CHEMICAL CO.,LTD

website:http://www.weichichem.com

Contact:+8613912949432

Address:Fine Chemical Industrial Base,Wujiang town,He County,Anhui China.
A-Chem Technologies Co.,Ltd.

Contact:+86-512-69561895

Address:No.111, Building A4, 218 Xinghu Street, Suzhou Industrial Park, P. R. China
Sinoway International (Jiangsu) Co., Ltd.

Contact:+86-25-86630167

Address:17 Beijing Road (West), Nanjing, China

Relevant to this article

A Diels-Alder crosslinkable host polymer for improved PLED performance: The impact on solution processed doped device and multilayer device performance

Doi:10.1039/c2jm14591j
(2012)
Utilizing an Encapsulated Solution of Reagents to Achieve the Four-Component Synthesis of (Benzo)Thiophene Derivatives

Doi:10.1002/adsc.201601343
(2017)
SmI2-PROMOTED KETYL RADICAL ADDITION TO O-BENZYL FORMALDOXIME. A NEW AMINOMETHYLATION

Doi:10.1016/0040-4039(91)80831-P
(1991)
Enantioselective total synthesis of the di-O-methyl ethers of (-)-agatharesinol, (+)-hinokiresinol and (-)-sugiresinol, characteristic norlignans of Coniferae

Doi:10.1039/P19960000405
(1996)
Asymmetric reductive amination of cycloalkanones. XI. Synthesis of optically active 2-substituted cycloheptanamines

Doi:10.1002/ardp.19913240604
(1991)
Palladium-catalyzed silyl C(sp³)-H bond activation

Doi:10.1039/c2ob06941e
(2012)

Article Doi