SYNTHESIS AND CONVERSIONS OF PIPERAZINE-2-CARBOXYLIC ACID

DOI: 10.1007/BF00515075

Source and publish data:

Chemistry of Heterocyclic Compounds p. 693 - 696 (1985)

Update date:2022-08-04

Topics: Synthesis Chemical formula Compound Piperazine Chemical Reaction Experimental Organic compound Conversions

Authors:

Kutina, N. N.

Zhikhareva, G. P.

Anisimova, O. S.

Yakhontov, L. N.

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Article abstract of DOI:10.1007/BF00515075

A method has been developed for the synthesis of methyl piperazinium-2-carboxylate dihydrochloride (overall yield 46percent) and piperazinium-2-carboxylic acid dihydrochloride (overall yield 36percent), from ethylene diamine through N,N'-di(trifluoroacetyl)ethylenediamine and methyl N,N'-di(trifluoroacetyl)piperazine-2-carboxylate.The N,N'-dinitroso derivatives were synthesized.

Full text of DOI:10.1007/BF00515075

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