Journal of the American Chemical Society p. 3679 - 3682 (2012)
Update date:2022-08-03
Topics:
Wang, Yi-Feng
Zhu, Xu
Chiba, Shunsuke
A method for the synthesis of bi- and tricyclic amidines has been developed through copper-catalyzed aerobic [3+2]-annulation reaction of N-alkenyl amidines. These cyclic amidines could be converted into mono-benzyl-protected vicinal diamines by the reduction with aluminum hydride.
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