Tetrahedron Letters p. 3421 - 3424 (1991)
Update date:2022-08-05
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Cerovsky, Vaclav
Free Staphylococcus aureus V8 proteinase was applied to coupling reactions of Z-Glu-OMe, Z-Glu-OBzl, Z-Ala-Glu-OMe, and Z-Ala-Ala-Glu-OMe with various amino acid amides and peptides in acetonitrile containing 5 vol. percent of water.No synthesis of Z-Asp-Leu-NH2 was achieved under the same conditions.The synthesis of Z-Glu-Leu-NH2 proceeded analogously also in 2-propanol or tert-butanol.
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