
Synthesis p. 526 - 528 (1991)
Update date:2022-07-30
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N-Alkoxycarbonyl-L-homoserine lactones (α-alkoxycarbonyl-amino-γ-butyrolactones) were prepared by selective esterification of L-aspartatic acid followed by N-protection, precipitation of the dicyclohexylammonium salts, chemoselective reduction with lithium borohydride, and cyclization to the corresponding γ-lactones during isolation.
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