Core structure-based design of organocatalytic [3+2]-cycloaddition reactions: Highly efficient and stereocontrolled syntheses of 3,3′-pyrrolidonyl spirooxindoles

Article abstract of DOI:10.1002/chem.201103449

Extraordinary levels of stereocontrol were achieved in an efficient organocatalytic asymmetric [3+2]-cycloaddition reaction between an α-isothiocyanato imide and various methyleneindolinones. Simple precursors were used for the rapid construction of spiro