Symbiotic approach to drug design: N-propanolamine derivatives as β-adrenergic blocking agents with diuretic activity

Article abstract of DOI:10.1016/0223-5234(91)90098-8

A series of oxypropanolamines and iminoxypropanolamines, in which the aminic substituent was the 2-(4-chloro-3-sulfamoylbenzamido)-ethyl group, were synthesized as potential β-blocker/diuretic agents.All of these compounds were tested for β₁-ad