6-Nitrobenzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (NBOP): A new coupling reagent in oligonucleotide synthesis

Article abstract of DOI:10.1080/15257779408011879

6-Nitrobenzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (NBOP, 2) has been demonstrated as an efficient coupling reagent in oligonucleotide synthesis. The reagent is stable and gives high coupling yields without any side products.

Full text of DOI:10.1080/15257779408011879

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6-N-1 Trobenzotriazol-1-
Yloxytris(Dimethylamino)Phosphonium
Hexafluorophosphate (NBOP): A New
Coupling Reagent in Oligonucleotide
Synthesis
S. A. Nadeem Hashmi a , M. Adiraj a , Anil Kumar a & S. B. Katti a
a Division of Biopolymers , Central Drug Research Institute ,
Lucknow, India
Published online: 24 Sep 2006.
To cite this article: S. A. Nadeem Hashmi , M. Adiraj , Anil Kumar & S. B. Katti (1994) 6-N-1
Trobenzotriazol-1-Yloxytris(Dimethylamino)Phosphonium Hexafluorophosphate (NBOP): A New
Coupling Reagent in Oligonucleotide Synthesis, Nucleosides and Nucleotides, 13:5, 1059-1067, DOI:
10.1080/15257779408011879
To link to this article: http://dx.doi.org/10.1080/15257779408011879
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